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Imbalance of regulatory T cells in human autoimmune diseases

✍ Scribed by Christian Dejaco; Christina Duftner; Beatrix Grubeck-Loebenstein; Michael Schirmer

Book ID: 108781827
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 145 KB
Volume: 117
Category: Article
ISSN: 0019-2805
DOI: 10.1111/j.1365-2567.2005.02317.x

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## Abstract CD4^+^CD25^+^ regulatory T cells (Treg) appear to be critical in regulating immune responses to self‐antigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mecha