𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Imaging reactive oxygen species in asthma

✍ Scribed by Vachier, Isabelle ;Doucen, Christian Le ;Loubatière, Jacques ;Damon, Marcelle ;Térouanne, Béatrice ;Nicolas, Jean-Claude ;Chanez, Pascal ;Godard, Philippe

Publisher
John Wiley and Sons
Year
1994
Weight
399 KB
Volume
9
Category
Article
ISSN
0884-3996

No coin nor oath required. For personal study only.

✦ Synopsis

Inflammatory processes in asthma are characterized by an infiltration o f inflammatory cells including mononuclear phagocytes. It has been observed that mononuclear phagocytes, alveolar macrophages and blood monocytes, release higher quantities o f reactive oxygen species in asthmatic patients than in healthy subjects. Chemiluminescence assays were developed t o measure the superoxide anion and the other reactive oxygen species. The chemiluminescence response was first analysed w i t h a luminometer, which made it possible t o study cells in suspension before and after PMAstimulation. Secondly a video-imaging camera was used in experiments on adherent cells before and after stimulation with PMA and/or specific stimulus IgE/anti-lgE. Both techniques showed t h a t human alveolar macrophages, blood monocytes, PMN and lymphocytes were spontaneously primed in vivo and were more easily stimulated in asthma. Analysis o f adherent cells in vitro may provide give information on the physiological condition o f adherent cells in vivo.

📜 SIMILAR VOLUMES

In utero–initiated cancer: The role of r
In utero–initiated cancer: The role of reactive oxygen species
✍ Joanne Wan; Louise M. Winn 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB 👁 1 views

It is becoming more evident that not only can drugs and environmental chemicals interfere with normal fetal development by causing structural malformations, such as limb defects, but that xenobiotic exposure during development can also cause biochemical and functional abnormalities that may ultimate

Reactive oxygen species are involved in
Reactive oxygen species are involved in nickel inhibition of DNA repair
✍ S. Lynn; F. H. Yew; K. S. Chen; K. Y. Jan 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 123 KB 👁 1 views

Nickel has been shown to inhibit DNA repair in a into the DNase I-activated calf thymus DNA was way that may play a role in its toxicity. Since nickel stronger than the ligation of poly(dA)roligo(dT), treatment increases cellular reactive oxygen species whereas H 2 O 2 was more potent in inhibiting

Reactive oxygen species as mediators of
Reactive oxygen species as mediators of the transformed phenotype
✍ Juliane M. Jürgensmeier; Jens Panse; Reinhold Schäfer; Georg Bauer 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 64 KB 👁 1 views

Reactive oxygen species (ROS) are known to be involved in different pro- and anticarcinogenic mechanisms. However, their influence on the maintenance of the transformed phenotype has not been studied so far. Here we show that the anchorage-independent growth of transformed murine fibroblasts is inhi

Scavenging effects of phenolic compounds
Scavenging effects of phenolic compounds on reactive oxygen species
✍ Hassan Y. Aboul-Enein; Irena Kruk; Aleksandra Kładna; Krzysztof Lichszteld; Tere 📂 Article 📅 2007 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 235 KB 👁 1 views

## Abstract Phenolic compounds are widely present in plants and they have received considerable attention due to their antioxidant property. In this article we report the results of a study of the reactivity of 10 selected phenolics (sesamol, three phenolic acids, three flavonols, one flavone, and