Formation and detoxification of reactive oxygen species
✍ Scribed by Radosława Kuciel; Aleksandra Mazurkiewicz
- Publisher
- The American Society for Biochemistry and Molecular Biology
- Year
- 2004
- Tongue
- English
- Weight
- 127 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1470-8175
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Inflammatory processes in asthma are characterized by an infiltration o f inflammatory cells including mononuclear phagocytes. It has been observed that mononuclear phagocytes, alveolar macrophages and blood monocytes, release higher quantities o f reactive oxygen species in asthmatic patients than
## Nitric oxide (NO) and reactive oxygen species (ROS) are important mediators in the pathogenesis of inflammatory bowel disease (IBD). NO in IBD can be either harmful or protective. NO can react with superoxide anions (O 2 • ), yielding the toxic oxidizing agent peroxynitrite (ONOO ). Peroxynitri