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Imaging and Sequencing Single Molecules in Individual Cells

โœ Scribed by Xie, Sunney


Book ID
122251030
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
37 KB
Volume
104
Category
Article
ISSN
0006-3495

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## Abstract **One's enough**: The direct observation of a DNAโ€polymeraseโ€based โ€œsequencing engineโ€ using singleโ€molecule detection recently allowed singleโ€molecule sequencing by synthesis in real time. Nucleotides with a fluorescent marker at the 5โ€ฒโ€phosphate unit and zeroโ€mode waveguides are cruci