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IL-2Rβ Links IL-2R Signaling with Foxp3 Expression

✍ Scribed by David Soper

Book ID
113539694
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
43 KB
Volume
123
Category
Article
ISSN
1090-2341

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IL-2Rβ links IL-2R signaling with Foxp3
IL-2Rβ links IL-2R signaling with Foxp3 expression
✍ David M. Soper; Deborah J. Kasprowicz; Steven F. Ziegler 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 401 KB

## Abstract Immunological tolerance to self antigens is a tightly regulated process. Recent work has demonstrated that the forkhead family member Foxp3 is a critical element in the differentiation and function of mouse CD4^+^CD25^+^ regulatory T cells (Treg). Recent work has suggested an important