𝔖 Bobbio Scriptorium
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Sa.52. The Role of IL2Rβ in Foxp3 Expression and Generation of TR Cells

✍ Scribed by David Soper; Deborah Kasprowicz; Steven Ziegler

Book ID
116366585
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
43 KB
Volume
119
Category
Article
ISSN
1090-2341

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## Abstract CD4^+^Foxp3^+^ Treg consist of two indistinguishable subsets induced in either the thymus or the periphery. In addition to their suppressive activities, IL‐6 can convert natural Treg to pro‐inflammatory IL‐17‐producing cells, but those induced with IL‐2 and TGF‐β remain Treg. Unlike mou