Mann-Whitney U-test were used for statistical analysis.
A total of 618 IBD patients (CD 485, UC 125, indeterminate colitis [IC] 8) were included in our study (Table 1). Venous TE was diagnosed in 38 (6.2%) patients (CD 27, UC 11). Distribution of gender and diagnosis of IBD (CD, UC, or IC) did not differ between patients with and without venous TE. Furthermore, thrombotic complications were not associated with colonic involvement, neither in CD nor in UC. CD patients with and without TE were diagnosed to have colonic involvement in 85.2% and 84.5%, respectively (NS). Extensive colitis was found in 54.5% and 54.9% of UC patients with and without TE, respectively (NS). For calculation of disease extension, patients with UC and IC were included in one group. However, patients with a history of venous TE were older and had a longer duration of disease (Table 1). Furthermore, intestinal resections were performed more often in CD patients with TE. There was no difference according to colectomy in UC patients.
In our large study population colonic involvement in IBD patients did not predispose to thromboembolism. The majority of both patients with and without TE had colonic involvement in CD and extensive UC, respectively. However, venous TE was associated with the well-known thrombotic risk factor of older age as well as longer duration of disease and intestinal resections in CD.