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IL-12 + rituximab well tolerated in B-cell non-Hodgkin's lymphoma

Book ID
120864669
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2002
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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Rituximab is a chimeric anti CD-20 monoclonal antibody containing human IgG1 kappa constant regions, with murine variable regions. The anti-lymphoma effects of Rituximab are probably due to complement and antibody-dependent cell-mediated cytotoxicity, and induction of apoptosis. Phase II trials have