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IL-12 gene therapy for cancer: in synergy with other immunotherapies

✍ Scribed by Ignacio Melero; Guillermo Mazzolini; Iñigo Narvaiza; Cheng Qian; Lieping Chen; Jesús Prieto

Book ID
117786821
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
72 KB
Volume
22
Category
Article
ISSN
1471-4906

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## Abstract Interleukin‐12 (IL‐12) is effective in treating many types of rodent tumors, but has been unsuccessful in most human clinical trials, suggesting that animal models of more clinical relevance are required for evaluating human cancer immunotherapy. Herein, we report on the effectiveness o