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IgM antibodies to GD1b, GT1b and GD3 and IgG antibodies to GD1a in two patients with chronic sensory demyelinating neuropathy

✍ Scribed by V. Andrés Maria; S. Olga; S. Roberto; S. Gustavo; L. Pablo; H. Gustavo

Book ID
114138746
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
139 KB
Volume
90
Category
Article
ISSN
0165-5728

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Antibodies to GM1 and GD1b in patients with motor neuron disease without plasma cell dyscrasia
✍ Dr. Michael E. Shy; Vance A. Evans; Fred D. Lublin; Robert L. Knobler; Terry Hei 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 464 KB 👁 2 views

Fifty-nine percent of 49 patients with motor neuron disease and 25% of 91 control subjects had IgM antibodies to ganglioside GM1 but usually not to GDlb at titers less than 1:80. This suggests that antibodies to GM1 may be part of the normal human antibody repertoire. However, given the higher incid