IgA rheumatoid factor synthesis by dissociated synovial cells. Characterization and relationship to IgM rheumatoid factor synthesis
β Scribed by William J. Koopman; Ralph E. Schrohenloher; Sylvia S. Crago; David M. Spalding; Jiri Mestecky
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 819 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0004-3591
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## Abstract In an indirect hemolytic plaque assay that used sheep erythrocytes coated with normal rabbit IgG or reduced/alkylated IgG antiβsheep erythrocytes, mononuclear cells eluted from rheumatoid synovial tissue of 7 of 11 patients with seropositive rheumatoid arthritis contained cells that sec
Eleven patients with active rheumatoid arthritis were monitored prospectively while receiving up to 1 gm of gold sodium thiomalate. There was a significant decrease in serum and synovial fluid IgG, IgA, and IgM rheumatoid factor (RF) levels over the period of study. Comparison of changes in serum RF