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IDENTIFICATION OF TWO NEW α-THALASSEMIA MUTATIONS IN EXON 2 OF THE α1-GLOBIN GENE

✍ Scribed by Waye, John S.; Eng, Barry; Patterson, Margaret; Carcao, Manuel D.; Chang, Lebe; Olivieri, Nancy F.; Chui, David H. K.


Book ID
127328071
Publisher
Informa plc
Year
2001
Tongue
English
Weight
99 KB
Volume
25
Category
Article
ISSN
0363-0269

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Analysis of alpha-thalassemia syndromes in several German families revealed DNA deletion as well as non-deletion forms as the molecular basis for the defects. Thus, the alpha-thalassemia haplotype was identified as the (-alpha)3.7 rightward deletion form, and the region of the putative recombination