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Characterization of Two Unique α-Globin Gene Cluster Deletions Causing α-Thalassemia in Israeli Arabs

✍ Scribed by Gilad, Oded; Dgany, Orly; Noy-Lotan, Sharon; Krasnov, Tania; Elitzur, Sarah; Pissard, Serge; Kventsel, Iris; Yacobovich, Joanne; Tamary, Hannah


Book ID
126887885
Publisher
Informa plc
Year
2014
Tongue
English
Weight
484 KB
Volume
38
Category
Article
ISSN
0363-0269

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α-Globin gene deletion causes α-thalasse
✍ Jürgen Horst; Ernst-Ulrich Griese; Enno Kleihauer; Elisabeth Kohne 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 331 KB

Restriction endonuclease mapping of chromosomal DNA has been used to determine whether the alpha-globin gene deletion or non-deletion form of alpha-thalassemia is the underlying molecular defect in individuals of two unrelated German families with alpha-thalassemia syndromes. The obtained DNA patter