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Identification of Tri- and Tetracyclic Pyrimidinediones as Sirtuin Inhibitors

✍ Scribed by Dante Rotili; Domenico Tarantino; Vincenzo Carafa; Ester Lara; Sarah Meade; Giorgia Botta; Angela Nebbioso; Jörg Schemies; Manfred Jung; Aleksey G. Kazantsev; Manel Esteller; Mario F. Fraga; Lucia Altucci; Antonello Mai


Book ID
102105307
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
426 KB
Volume
5
Category
Article
ISSN
1860-7179

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✍ V.V Veselovsky; V.A Dragan; A.M Moiseenkov 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 211 KB

Low-temperature boron trifluoride etherate initiated cyclization of o(-geraniol, d-nerol, and d-linalool leads to regioisomeric dimethylvinylcyclohexenes possessing a rare monoterpene carbon skeleton along with bicyclou.2.1]octyl fluoride. The cyclization mimics biosynthesis of tri-and tetracyclic d