Identification of the TAF15–ZNF384 fusion gene in two new cases of acute lymphoblastic leukemia with a t(12;17)(p13;q12)
✍ Scribed by Kaja Beate Nyquist; Jim Thorsen; Bernward Zeller; Alf Haaland; Gunhild Trøen; Sverre Heim; Francesca Micci
- Book ID
- 116332572
- Publisher
- Elsevier
- Year
- 2011
- Tongue
- English
- Weight
- 398 KB
- Volume
- 204
- Category
- Article
- ISSN
- 2210-7762
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## Abstract The chimeric gene __NUP98/HOXC13__ was detected in a patient with a de novo acute myeloid leukemia and a t(11;12)(p15;q13). Fluorescence in situ hybridization with PAC1173K1 identified the breakpoint on 11p15, indicating that the __NUP98__ gene was involved in the translocation. At 12q1