𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Identification of a novel fusion gene, TTL, fused to ETV6 in acute lymphoblastic leukemia with t(12;13)(p13;q14), and its implication in leukemogenesis

✍ Scribed by Qiao, Y; Ogawa, S; Hangaishi, A; Yuji, K; Izutsu, K; Kunisato, A; Imai, Y; Wang, L; Hosoya, N; Nannya, Y

Book ID
110055464
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
338 KB
Volume
17
Category
Article
ISSN
0887-6924

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Fusion of TEL/ETV6 to a novel ACS2 in my
Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)
✍ Fumiharu Yagasaki; Itsuro Jinnai; Satoru Yoshida; Yasuko Yokoyama; Akira Matsuda πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 496 KB πŸ‘ 3 views

We identified a novel human long fatty acyl CoA synthetase 2 gene, ACS2, as a new ETV6 fusion partner gene in a recurrent t(5;12)(q31;p13) translocation in a patient with refractory anemia with excess blasts (RAEB) with basophilia, a patient with acute myelogenous leukemia (AML) with eosinophilia, a

Identification of a SRC-like tyrosine ki
Identification of a SRC-like tyrosine kinase gene, FRK, fused with ETV6 in a patient with acute myelogenous leukemia carrying a t(6;12)(q21;p13) translocation
✍ Noriko Hosoya; Ying Qiao; Akira Hangaishi; Lili Wang; Yasuhito Nannya; Masashi S πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 637 KB

## Abstract The SRC family of kinases is rarely mutated in primary human tumors. We report the identification of a SRC‐like tyrosine kinase gene, __FRK__ (Fyn‐related kinase), fused with __ETV6__ in a patient with acute myelogenous leukemia carrying t(6;12)(q21;p13). Both reciprocal fusion transcri

A novel cryptic translocation t(12;17)(p
A novel cryptic translocation t(12;17)(p13;p12–p13) in a secondary acute myeloid leukemia results in a fusion of the ETV6 gene and the antisense strand of the PER1 gene
✍ Eva Maria Murga Penas; Jan Cools; Petra Algenstaedt; Kristina Hinz; Doris Seeger πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 175 KB

The ETV6 gene is a member of the ETS family of transcription factors and the main target of chromosomal rearrangements affecting chromosome band 12p13. To date, more than 15 fusion partners of ETV6 have been characterized at the molecular level. Most of these fusions encode chimeric proteins with on

A t(6;12)(q23;p13) results in the fusion
A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line
✍ Yoshimasa Suto; Yuko Sato; Stephen D. Smith; Janet D. Rowley; Stefan K. Bohlande πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 807 KB

ETV6 (TEL) is rearranged in various types of hematologic malignancies. The B-cell precursor acute lymphoblastic leukemia (ALL) cell line SUP-B2 has a t(6;12)(q23;p13) involving ETV6 at 12p13 and a submicroscopic deletion of the other ETV6 allele. The reciprocal translocation results in the fusion of