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Identification of the active metabolite of ticlopidine from rat in vitro metabolites

✍ Scribed by Kenji Yoneda; Ryou Iwamura; Hiroko Kishi; Yoichi Mizukami; Kimiko Mogami; Sei Kobayashi


Book ID
110008330
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
164 KB
Volume
142
Category
Article
ISSN
0007-1188

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The urinary metabolites of flavanone in the rat were investigated using a gas chromatographic mass spectrometric method employing an OV-1 capillary column. Forty-three metabolites were detected and the most prominent of these were identified. The most common metabolic reactions were reduction of the