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Identification of methionyl and cysteinyl residues in the substrate binding site of carboxypeptidase Y

✍ Scribed by Klaus Breddam; IB Svendsen

Publisher
Springer-Verlag
Year
1984
Weight
474 KB
Volume
49
Category
Article
ISSN
0105-1938

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📜 SIMILAR VOLUMES

Identification of the catalytic histidin
Identification of the catalytic histidine residue participating in the charge-relay system of carboxypeptidase Y
✍ Giman Jung; Hiroshi Ueno; Rikimaru Hayashi; Ta-Hsiu Liao 📂 Article 📅 1995 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 262 KB

## Abstract The essential histidine residue of carboxypeptidase Y (CPY) was modified by a site‐specific reagent, a chloromethyl‐ketone derivative of benzyloxycarbonyl‐L‐phenylalanine. The single modified histidine residue was converted to __N__τ ‐carboxymethyl histidine (cmHis) upon performic acid