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Identification of hepatitis A virus mimotopes by phage display, antigenicity and immunogenicity

✍ Scribed by Osmany G. Larralde; Raiza Martinez; Frank Camacho; Nevis Amin; Alicia Aguilar; Arturo Talavera; David I. Stott; Ela M. Perez

Book ID: 113767441
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 403 KB
Volume: 140
Category: Article
ISSN: 0166-0934
DOI: 10.1016/j.jviromet.2006.10.015

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## Abstract The hypervariable region 1 (HVR1) is the target of neutralizing antibodies but with isolate specificity. The aim of this study was to obtain immunogenic mimotopes of HVR1, which can react broadly with different HVR1 antibodies and could be one of the candidate immunogens in an effective