Antigenic and immunogenic mimicry of the HER2/neu oncoprotein by phage-displayed peptides

Analysis of the CD2 and spliceosomal Sm

Analysis of the CD2 and spliceosomal Sm B/B′ polyproline-arginine motifs defined by a monoclonal antibody using a phage-displayed random peptide library

✍ Dimitri Monos; John Heliopoulos; Elias Argyris; Paul Cordopatis; Aikaterini Zomp 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB 👁 1 views

The cytoplasmic region of the CD2 receptor of lymphocytes contains proline-rich motifs, which are involved in T cell activation and interleukin-2 production. An intracellular CD2 binding protein, CD2BP2, interacts with two tandem PPPPGHR segments of the CD2 tail. CD2BP2 contains a GYF (glycine-tyros