A mimotope of Pre-S2 region of surface antigen of viral hepatitis B screened by phage display
β Scribed by Zhang, WU Yu; WAN, Ying; LI, Dao Guo; TANG, Yan; ZHOU, Wei
- Book ID
- 110020450
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 271 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0007-0610
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## Abstract We constructed a recombinant plasmid that can express the entire preβS2 sequence of hepatitis B surface antigen (HBsAg) as a fusion protein in __E. coli__. The hybrid protein, which comprises the bacterial TrpLE protein and the preβS2 sequence, was the prominent protein that was found i
## Abstract The hypervariable region 1 (HVR1) is the target of neutralizing antibodies but with isolate specificity. The aim of this study was to obtain immunogenic mimotopes of HVR1, which can react broadly with different HVR1 antibodies and could be one of the candidate immunogens in an effective