Identification of Genes Associated with Tumor Suppression in Syrian Hamster Embryo Cells
β Scribed by Roger W. Wiseman, Jeffry C. Montgomery, Junichi Hosoi, Esther W. Hou, Charles J. Cochran, Patricia W. Lamb and J. Carl Barrett
- Book ID
- 124310831
- Publisher
- Environmental Health Information Service
- Year
- 1991
- Tongue
- English
- Weight
- 302 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0091-6765
- DOI
- 10.2307/3431177
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Carcinogen-induced transformation in Syrian hamster embryo (SHE) cells is a multistage process characterized by specific genetic alterations at each stage in the transformation process. Loss of H19 gene expression is one of the earliest events observed, occurring in approximately 75% of the morpholo
We previously described the isolation of closely related, preneoplastic Syrian hamster cell lines that have retained (supB+) or lost (supB-) the ability to suppress the anchorage-independent growth and tumorigenicity of a sarcoma cell line (BP6T) in cell hybrids. In this report, we have used differe