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Cytotoxic and transforming effects of silica particles with different surface properties in Syrian hamster embryo (SHE) cells

✍ Scribed by Z Elias; O Poirot; M.C Danière; F Terzetti; A.M Marande; S Dzwigaj; H Pezerat; I Fenoglio; B Fubini


Book ID
117587364
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
242 KB
Volume
14
Category
Article
ISSN
0887-2333

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To examine a direct involvement of genotoxic effects of estrogens in the initiation of hormonal carcinogenesis, the abilities of 17beta-estradiol (E2) and 8 of its metabolites to induce cellular transformation and genetic effects were studied using the Syrian hamster embryo (SHE) cell model. Treatme