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Identification of gene expression changes in transgenic C. elegans overexpressing human α-synuclein

✍ Scribed by Suvi Vartiainen; Petri Pehkonen; Merja Lakso; Richard Nass; Garry Wong

Book ID
113811976
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
470 KB
Volume
22
Category
Article
ISSN
0969-9961

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## Abstract Parkinson's disease is neuropathologically characterized by the presence of Lewy bodies, whose major component is α‐synuclein. We had previously generated transgenic mice that expressed human α‐synuclein carrying an Ala53Thr point mutation (hα‐syn140m) under the control of the rat tyros