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Behavioral effects of dopaminergic agonists in transgenic mice overexpressing human wildtype α-synuclein

✍ Scribed by S.M. Fleming; J. Salcedo; C.B. Hutson; E. Rockenstein; E. Masliah; M.S. Levine; M.-F. Chesselet

Book ID
116787921
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
189 KB
Volume
142
Category
Article
ISSN
0306-4522

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## Abstract Parkinson's disease is neuropathologically characterized by the presence of Lewy bodies, whose major component is α‐synuclein. We had previously generated transgenic mice that expressed human α‐synuclein carrying an Ala53Thr point mutation (hα‐syn140m) under the control of the rat tyros