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Identification of an Orally Active Opioid Receptor-like 1 (ORL1) Receptor Antagonist 4-{3-[(2 R )-2,3-Dihydroxypropyl]-2-oxo-2,3-dihydro-1 H -benzimidazol-1-yl}-1-[(1 S ,3 S ,4 R )-spiro[bicyclo[2.2.1]heptane-2,1′-cyclopropan]-3-ylmethyl]piperidine as Clinical Candidate

✍ Scribed by Satoh, Atsushi; Sagara, Takeshi; Sakoh, Hiroki; Hashimoto, Masaya; Nakashima, Hiroshi; Kato, Tetsuya; Goto, Yasuhiro; Mizutani, Sayaka; Azuma-Kanoh, Tomoko; Tani, Takeshi; Okuda, Shoki; Okamoto, Osamu; Ozaki, Satoshi; Iwasawa, Yoshikazu; Ohta, Hisashi; Kawamoto, Hiroshi

Book ID: 126854945
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 841 KB
Volume: 52
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm900581g

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