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Identification of a YAC spanning the translocation breakpoint t(8;22) associated with acute monocytic leukemia

✍ Scribed by Valérie Soenen; Max Chaffanet; Claude Preudhomme; Amel Dib; Jean-Luc Laï; Jonathan A. Fletcher; Daniel Birnbaum; Marie-Josèphe Pébusque

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
300 KB
Volume
15
Category
Article
ISSN
1045-2257

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✦ Synopsis

Using a series of yeast artificial chromosomes (YAC) from the 8p I I -I 2 chromosome region, we have analyzed a t(822) translocation present in two patients suffering from acute leukemia by using fluorescence in situ hybridization (FISH). We have identified a YAC that spans the breakpoint in both cases. Genes Chromosom Concer 15: 191-194 (1996).

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