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Identification of a rare e8a2 BCR-ABL fusion gene in three novel chronic myeloid leukemia patients treated with imatinib

✍ Scribed by Cayuela, J M; Rousselot, P; Nicolini, F; Espinouse, D; Ollagnier, C; Bui-Thi, M H; Chabane, K; Raffoux, E; Callet-Bauchu, E; Tigaud, I


Book ID
110056507
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
99 KB
Volume
19
Category
Article
ISSN
0887-6924

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Since very few unusual BCR/ABL fusion transcripts in chronic myeloid leukemia have been reported, no clear evidence exists concerning their clinical and prognostic implications. We describe here a CML case with normal karyotype at standard cytogenetics and an atypical e6a2 BCR/ABL fusion transcript,