In serum-free primary culture of dissociated mouse epidermal cells, a-melanocyte stimulating hormone (a-MSH) and dibutyryl cyclic AMP (UBcAMP) induced the differentiation of melanocytes. Moreover, the proliferation of melanocytes was also induced in the dishes cultured with DECAMP, but not with a-MS
Identification of a phytochemical stimulant for the proliferation of mouse melanocytes in culture
✍ Scribed by A. Raman; Z. Lin; J. R. S. Hoult
- Book ID
- 111756996
- Publisher
- Pharmaceutical Press
- Year
- 1998
- Tongue
- English
- Weight
- 83 KB
- Volume
- 50
- Category
- Article
- ISSN
- 2042-7158
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## Abstract The epidermal cell suspensions of the neonatal dorsal skin derived from wild type mouse at the pink‐eyed dilution (__p__) locus (black, C57BL/10JHir‐__P/P__) and their congenic mutant mouse (pink‐eyed dilution, C57BL/10JHir‐__p/p__) were cultured with a serum‐free melanocyte growth medi
## Abstract Mouse epidermal melanoblasts/melanocytes preferentially proliferated from disaggregated epidermal cell suspensions derived from newborn mouse skin in a serum‐free melanoblast/melanocyte‐proliferation medium supplemented with dibutyryl adenosine 3′:5′‐cyclic monophosphate (DBcAMP) and/or