Granulocyte–macrophage colony-stimulating factor is a keratinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture
✍ Scribed by Tomohisa Hirobe; Rikako Furuya; Ohji Ifuku; Masatake Osawa; Shin-ichi Nishikawa
- Book ID
- 116981007
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 651 KB
- Volume
- 297
- Category
- Article
- ISSN
- 0014-4827
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## Abstract Mouse epidermal melanoblasts/melanocytes preferentially proliferated from disaggregated epidermal cell suspensions derived from newborn mouse skin in a serum‐free melanoblast/melanocyte‐proliferation medium supplemented with dibutyryl adenosine 3′:5′‐cyclic monophosphate (DBcAMP) and/or
## Abstract The roles of colony‐stimulating factors in long‐term bone marrow cultures were studied and compared. After single additions of high concentrations of unpurified colony‐stimulating activities to the cultures, rapid deterioration of the cultures was observed. This appears to result from c