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Identification of a peptide binding motif for secreted frizzled-related protein-1

✍ Scribed by Yoshiro Chuman; Aykut Üren; Jennifer Cahill; Carole Regan; Vladimir Wolf; Brian K. Kay; Jeffrey S. Rubin


Book ID
116830520
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
235 KB
Volume
25
Category
Article
ISSN
0196-9781

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✍ Ramesh A. Bhat; Barbara Stauffer; Barry S. Komm; Peter V.N. Bodine 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

## Abstract Secreted frizzled‐related proteins (sFRPs) are glycoproteins that are recognized as Wnt antagonists. To identify the functional domains that are involved in Wnt antagonist function, several sFRP‐1 mutants and sFRP‐1/sFRP‐2 chimeras were generated. These mutants were characterized in an