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Identification of a novelNBNtruncating mutation in a family with hereditary prostate cancer

✍ Scribed by Kimberly A. Zuhlke,Anna M. Johnson,Linda A. Okoth,Elena M. Stoffel…


Book ID
126355412
Publisher
Springer Netherlands
Year
2012
Tongue
English
Weight
395 KB
Volume
11
Category
Article
ISSN
1389-9600

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## BACKGROUND. Two genes responsible for hereditary breast cancer (BRCA1 and BRCA2) have been identified, and predisposing mutations identified. Several studies have provided evidence that germline mutations in BRCA1 and BRCA2 confer an increased risk of prostate cancer. Based on these findings, o