1β£,25-Dihydroxyvitamin D 3 has been shown to exert its effects by both genomic (minutes to hours) and rapid (seconds to minutes) mechanisms. The genomic effects are mediated by interaction with the nuclear vitamin D receptor. We show that the vitamin D analog, [ 14 C]-1β£,25-dihydroxyvitamin D 3 brom
β¦ LIBER β¦
Identification of a Membrane Receptor for 1,25-Dihydroxyvitamin D3 Which Mediates Rapid Activation of Protein Kinase C
β Scribed by I. Nemere; Z. Schwartz; H. Pedrozo; V. L. Sylvia; D. D. Dean; B. D. Boyan
- Book ID
- 111486388
- Publisher
- American Society for Bone and Mineral Research
- Year
- 1998
- Tongue
- English
- Weight
- 212 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0884-0431
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## Abstract The rapid, nonβgenomic actions of 1,25βdihydroxyvitamin D~3~ [1,25(OH)~2~D~3~] have been well described, however, the role of the nuclear vitamin D receptor (VDR) in this pathway remains unclear. To address this question, we used VDR(+/+) and VDR(β/β) osteoblasts isolated from wildβtype
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