In order to determine the regional localization of the Friedreich's ataxia (FA) gene on chromosome 9, the DNA probe DR47 (D9S5), which detects a restriction fragment length polymorphism (RFLP) in tight linkage with the disease, was hybridized in situ to metaphase chromosomes. Our results enable the
โฆ LIBER โฆ
Identification of a hypervariable microsatellite polymorphism within D9S15 tightly linked to Friedreich's ataxia
โ Scribed by Julie Wallis; Robert Williamson; Susan Chamberlain
- Book ID
- 104699046
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 319 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0340-6717
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Using the technique of amplified restriction fragment polymorphism (AFLP) analysis, and bulked segregant pools from F~2~ progeny of the cross __Lycopersicon esculentum__ (Cf9)ร__L. pennellii__, approximately 42 000 AFLP loci for tight linkage to the tomato __Cfโ9__ gene for resistance to __Cladospor