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Identification, Expression, and Pharmacology of a Cys23-Ser23 Substitution in the Human 5-HT2C Receptor Gene (HTR2C)

✍ Scribed by Jaakko Lappalainen; Li Zhang; Michael Dean; Murat Oz; Norio Ozaki; Da-hong Yu; Matti Virkkunen; Forrest Weight; Markku Linnoila; David Goldman


Book ID
115612606
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
446 KB
Volume
27
Category
Article
ISSN
0888-7543

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Association analysis between a Cys23ser
✍ Samochowiec, Jerzy; Smolka, Michael; Winterer, Georg; Rommelspacher, Hans; Schmi πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 13 KB πŸ‘ 2 views

Transgenic mice lacking a functional 5-HT 2c receptor gene are extremely susceptible to audiogenic seizures, suggesting that 5-HT 2c receptors mediate inhibition of neuronal network excitability. The present association study tested the hypothesis that a Cys23Ser substitution polymorphism within the