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IDENTICAL MITOCHONDRIAL DNA DELETION IN BLOOD AND MUSCLE

✍ Scribed by Johns, DonaldR.; Drachman, DanielB.; Hurko, Orest

Book ID
123304935
Publisher
The Lancet
Year
1989
Tongue
English
Weight
324 KB
Volume
333
Category
Article
ISSN
0140-6736

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The present study was conducted to determine the effects of acute overload exercise on mitochondrial DNA and the structure of skeletal muscles. Rats were forced to run for 20 min until reaching complete exhaustion. We detected the large-scale deletion (7052 bp) of mitochondrial DNA by the nested pol