Ibuprofen Transport into and through Skin from Topical Formulations: In Vitro–In Vivo Comparison
✍ Scribed by Herkenne, Christophe; Naik, Aarti; Kalia, Yogeshvar N; Hadgraft, Jonathan; Guy, Richard H
- Book ID
- 110049565
- Publisher
- Nature Publishing Group
- Year
- 2007
- Tongue
- English
- Weight
- 218 KB
- Volume
- 127
- Category
- Article
- ISSN
- 0022-202X
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A procedure was developed for the in vivo evaluation of the bioavailability of topical formulations containing a limited amount of the active drug product estimated as the rate and extent to which the drug i s released from the vehicle to the skin. It i s assumed that drug transfer follows Fick's la