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Permeation of topically applied caffeine through human skin – a comparison of in vivo and in vitro data

✍ Scribed by Sindy Trauer; Alexa Patzelt; Nina Otberg; Fanny Knorr; Christel Rozycki; Gabor Balizs; Rolf Büttemeyer; Michael Linscheid; Manfred Liebsch; Jürgen Lademann


Book ID
108642347
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
550 KB
Volume
68
Category
Article
ISSN
0306-5251

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The goal of this work was to establish, using biophysical characterization, that porcine ear skin in vitro is a valid model for its human counterpart. Specifically, stratum corneum (SC) barrier function was evaluated during its progressive removal by adhesive tape-stripping using the techniques of t