i(12p)-negative testicular germ cell tumors: A different group?
✍ Scribed by Sérgio M.M.J. Castedo; Bauke de Jong; J. Wolter Oosterhuis; Raquel Seruca; Vera J. Idenburg; Janneke Buist; Dirk T. Sleijfer
- Book ID
- 119103963
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 523 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0165-4608
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## Abstract A chromosome 12‐derived marker was seen in each of 3 testicular germ cell tumors that lacked the i(12p). An interesting feature of 2 of the markers was that the major part, including the centromere, of an acrocentric (a #13 and #14, respectively) was translocated onto 12p, resulting in
The i( I2p) chromosome has been shown to characterize more than 80% of male germ cell tumors (GCTs) and is an important diagnostic marker. Although recent cytogenetic analyses of GCTs have defined nonrandom chromosome abnormalities in these tumors, no attempt has so far been made to compare i( I2p)-