Hypomethylation of DNA and the insulin-like growth factor-II gene in dichloroacetic and trichloroacetic acid-promoted mouse liver tumors
โ Scribed by Lianhui Tao; Yingzhe Li; Paula M Kramer; Wei Wang; Michael A Pereira
- Book ID
- 108287072
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 309 KB
- Volume
- 196
- Category
- Article
- ISSN
- 0300-483X
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Insulin-like growth factor II (IGF-II) plays significant roles in the growth and development of mammals through the regulation of mitogenesis and cell survival. Previously, IGF-II mRNA transcripts within the CNS were detected in the choroid plexus and leptomeninges (DeChiara et al., 1991). The objec
We investigated expression of insulin-like growth factor II (Igf2) in primary cultured hepatocytes, liver epithelial (LE) cell lines derived from normal hepatocytes, and hepatocellular carcinoma (HCC) cell lines from crosses between C3H/HeJ (C3H) and Mus musculus molossinus mice (MSM). Igf2 mRNA was