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Hypofibrinogenemia in a girl with Langerhans cell histiocytosis during etoposide and prednisolone therapy

✍ Scribed by TAKUMA MIURA; MITSURU NAKAMURA; YUKIKO TSUNEMATSU; JUNICHIRO FUJIMOTO; TAKASHI MEGURO; KANEO YAMADA


Book ID
118711849
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
390 KB
Volume
35
Category
Article
ISSN
1328-8067

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πŸ“œ SIMILAR VOLUMES


Etoposide in the treatment of six childr
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Six children received etoposide as the single agent for treatment of Langerhans cell histiocytosis (LCH; histiocytosis X). Five were less than 2 years old at diagnosis. All had multiorgan involvement; one had liver and pulmonary dysfunction. Two infants also had clinical signs of immune deficiency.

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Viana et al. [I] described their experience with etoposide (VP-16) as initial therapy in the management of patients with Langerhans cell histiocytosis (LCH). However, caution should be used in advocating the use of an epipodophyllotoxin as the "drug of choice" for the treatment of this disorder. Alt

LCH-I: A randomized trial of etoposide v
✍ Ladisch, Stephan ;Gadner, Helmut ;Arico, Maurizio ;Broadbent, Valerie ;Grois, Ni πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 403 KB

## Abstract An international randomized trial in Langerhans cell histiocytosis (LCH) has been initiated by the Histiocyte Society. This report reviews the rationale, design, and progress of LCH‐I, which compares etoposide (VP‐16) and vinblastine in the treatment of disseminated LCH. Data on the ris