Hypersensitivity Reactions to Carboplatin: To the Editor
β Scribed by Maurie Markman
- Book ID
- 112248798
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 21 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0090-8258
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π SIMILAR VOLUMES
Carboplatin is the drug of choice for the treatment of nonresectable astrocytomas in children, but patients who are intolerant may require cranial irradiation which is associated with significant morbidity. Hypersensitivity reactions, including urticaria, bronchospasm, and hypotension, have been rep
## Background: Hypersensitivity reactions are rare but at times severe complications to cytostatic drugs. ## Procedure: The percentage of allergic reactions to carboplatin and their clinical features were evaluated in 185 children affected by different solid tumors and treated with etoposide-carb