Hypersensitivity Reactions to Carboplatin in Children
✍ Scribed by Ilaria Lazzareschi; Antonio Ruggiero; Riccardo Riccardi; Giorgio Attinà; Cesare Colosimo; Anna Lasorella
- Book ID
- 110341859
- Publisher
- Springer US
- Year
- 2002
- Tongue
- English
- Weight
- 350 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0167-594X
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📜 SIMILAR VOLUMES
## Background: Hypersensitivity reactions are rare but at times severe complications to cytostatic drugs. ## Procedure: The percentage of allergic reactions to carboplatin and their clinical features were evaluated in 185 children affected by different solid tumors and treated with etoposide-carb
Carboplatin is the drug of choice for the treatment of nonresectable astrocytomas in children, but patients who are intolerant may require cranial irradiation which is associated with significant morbidity. Hypersensitivity reactions, including urticaria, bronchospasm, and hypotension, have been rep