Hyperdimensional Protein NMR Spectroscopy in Peptide-Sequence Space
โ Scribed by Lescop, Ewen; Brutscher, Bernhard
- Book ID
- 126896034
- Publisher
- American Chemical Society
- Year
- 2007
- Tongue
- English
- Weight
- 165 KB
- Volume
- 129
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A combinatorial sequence space (CSS) model was introduced to represent sequences as a set of overlapping k-tuples of some fixed length which correspond to points in the CSS. The aim was to analyze clusterization of protein sequences in the CSS and to test various hypotheses about the possible evolut
in gain does not change the S/N ratio of the spectrum, since Paci and co-workers (1) have recently reported that selecboth the noise and signal are equally enhanced and digitized. tive-excitation pulse sequences (2-4), which are exten-Since digitizers are preceded by audio filters, which usually siv
## Abstract **The natural way**: A sensitive NMR spectroscopic method is developed to obtain wellโresolved twoโdimensional spectra (^15^Nโ^1^H and ^13^Cโ^1^H) for naturalโabundance (that is, without the need for isotopic enrichment) largeโmolecule samples, such as biopharmaceuticals. This method gi