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Proton-Detected Solid-State NMR Spectroscopy of Natural-Abundance Peptide and Protein Pharmaceuticals

✍ Scribed by Donghua H. Zhou; Gautam Shah; Charles Mullen; Dennis Sandoz; Chad M. Rienstra

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
581 KB
Volume
121
Category
Article
ISSN
0044-8249

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Proton-Detected Solid-State NMR Spectros
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✍ Donghua H. Zhou; Gautam Shah; Charles Mullen; Dennis Sandoz; Chad M. Rienstra 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 581 KB

## Abstract **The natural way**: A sensitive NMR spectroscopic method is developed to obtain well‐resolved two‐dimensional spectra (^15^N–^1^H and ^13^C–^1^H) for natural‐abundance (that is, without the need for isotopic enrichment) large‐molecule samples, such as biopharmaceuticals. This method gi

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.