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Hydrogenation in solid phase peptide synthesis. I. removal of product from the resin

✍ Scribed by James M. Schlatter; Robert H. Mazur


Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
134 KB
Volume
18
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


Hydrogenation of protected leucine enkep
✍ David A. Jones Jr. πŸ“‚ Article πŸ“… 1977 πŸ› Elsevier Science 🌐 French βš– 228 KB

In the preceding paper,1 a description of the remwal of a peptide esterified to a polystyrene resin by means of catalytic hydrogenation was presented. This method is unique in the literature concerning solid phase peptide synthesis in that blocking groups derived frcmn A-butyl alcohol are left intac

Solid-phase synthesis of larger peptides
✍ Ching-I Niu; Shi-Zhen Yang; An-Qing Ma; Yun-Neng Chen; Yong-Qing Jiang; Wei-Teh πŸ“‚ Article πŸ“… 1981 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 547 KB

## Synopsis Attachment of the side-chain carboxyl of the protected aspartic or glutamic acid ester to the resin support has been established for the solid-phase synthesis of the asparagine or glutamine peptide. After further elongation of the a-amino deprotected resin-bound peptide ester with prot

A rapid non-acidolytic method for deprot
✍ Mohmed K. Anwer; Arno F. Spatola πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 French βš– 227 KB

Ammonium for-mate aided catalytic transfer hydrogenation has been employed in the cleavage, and concommitant deprotection, of the pentapeptide leucine enkephalin from the Merrifield peptide resin under ambient conditions of temperature and pressure in a neutral medium.

Solid phase peptide synthesis. I. A mild
✍ G.L. Southard; G.S. Brooke; J.M. Pettee πŸ“‚ Article πŸ“… 1969 πŸ› Elsevier Science 🌐 French βš– 209 KB

Solid phase peptide synthesis a8 introduced by Merrifield' and modified by others2 is proving to be a valuable addition to the tools of the peptide chemist.