Hydrocortisone inhibition of glucuronyl transferase in newborn rats
โ Scribed by Barbara Jones
- Book ID
- 118534154
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- English
- Weight
- 186 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1097-6833
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๐ SIMILAR VOLUMES
Glucuronidation is the major pathway for elimination of acetaminophen, diverting it from the toxifying pathway catalyzed by cytochromes P-450. A genetic deficiency in bilirubin UDP-glucuronyl transferase may predispose humans and animals to the toxicity of drugs that are extensively glucuronidated,
Microsomal UDP-glucuronyl transferases (uridine-5'-diphosphateglucuronate glucuronyl transferase, acceptor unspecific, EC 2.4.1.17) function in detoxification of a wide range of aglycons containing phenolic, alcoholic, carboxylic or amino acceptor groups through formation of water-soluble glucuronic