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Hybrid FMT–CT imaging of amyloid-β plaques in a murine Alzheimer's disease model

✍ Scribed by Damon Hyde; Ruben de Kleine; Sarah A. MacLaurin; Eric Miller; Dana H. Brooks; Thomas Krucker; Vasilis Ntziachristos

Book ID
118491386
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
579 KB
Volume
44
Category
Article
ISSN
1053-8119

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## Abstract We performed three‐dimensional, high‐resolution magnetic resonance imaging (MRI) of fixed mouse brains to determine whether MRI can detect amyloid plaques in transgenic mouse models of Alzheimer's disease. Plaque‐like structures in the cortex and hippocampus could be clearly identified