## Abstract The identification of the gene for Huntington's disease (HD) has made it possible to diagnose patients with HD who present with unusual or atypical features. We describe a 41βyearβold man whose intial manifestation of HD was dominated by the presence of motor and vocal tics and other fe
Huntington disease associated with Alzheimer disease
β Scribed by Gerald C. McIntosh; H. Douglas Jameson; Dr. William R. Markesbery
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 836 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0364-5134
No coin nor oath required. For personal study only.
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Huntington's disease (HD) is a late-onset degenerative disorder of the central nervous system, caused by a dominantly inherited mutation in a gene on chromosome 4p. The identification of the trinucleotide repeat mutation responsible for this disorder has been an important step towards understanding
## Abstract There have been extraordinary advances in our knowledge of the underlying gene, the protein it encodes, various models of disease, and potential targets for effective therapies for Huntington disease. Huntington disease research has increased exponentially in the past 25 years, and we n