Humoral Factors in Host Defense || HLA-DR Region Proteins and Genes
โ Scribed by Strominger, J.L.
- Book ID
- 120531229
- Publisher
- Elsevier
- Year
- 1983
- Tongue
- English
- Weight
- 390 KB
- Edition
- 1
- Category
- Article
- ISBN
- 0127682201
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โฆ Synopsis
Humoral Factors in Host Defense
๐ SIMILAR VOLUMES
Key words: restriction fragment length polymorphism (RFLP), insulin gene 5' flanking polymorphism (5' FP), insulm gene 6.0-kb probe, Southern blotting, HLA-DBP band patterns, HLA-DQP band patterns, HLA-DR subtypes I NTROD UCTl ON A principal aim of the insulin-dependent diabetes mellitus (IDDM) comp
A three-allele polymorphic system is detectable by direct electrophoretic analysis of the amplified 5' untranslated und 5' flanking regions of the HLA-linked HSP70-1 gene. Single nucleotide differences at two sites, i.e., -110 and + 120, are responsible for changes in the bending pattern and, conseq